Swollen hands from hanging water/infusion are generally related to personal constitution, drug stimulation, drug allergy, drug extravasation and other factors, and it is recommended that patients judge according to the symptoms of swollen hands and target treatment to avoid affecting the therapeutic effect of the drugs.1, personal constitution: some patients with poor peripheral circulation and renal insufficiency can have swollen hands because of slow metabolism of the organism and poor absorption of drugs and water, and also the phenomenon of edema in other parts of the organism, which is a normal phenomenon. Phenomenon, but also other parts of the body edema, is a normal phenomenon of the body, too swollen people can be under the guidance of the doctor to apply furosemide treatment; 2, drug stimulation: in the infusion, due to the different causes of each patient’s disease, the use of drugs there will be a certain degree of difference, some of the drugs on the vascular irritation of the blood vessels will be greater, infusion will be a slight pain, which may lead to swelling of the hands. If the swelling is not very obvious, then you can slow down the speed of hanging water, if the swelling is more obvious, you need to inform the medical staff in time, stop the infusion, and cold compresses on the swollen parts to promote the contraction of blood vessels, to avoid further aggravation of the swelling; 3, drug allergy: part of the population in the use of certain medications, an allergic reaction, resulting in swelling of the hands, this situation is generally accompanied by itching, redness, rash and other symptoms, and in severe cases, respiratory distress may occur. This condition is usually accompanied by skin itching, redness, rash and other symptoms, and in severe cases, respiratory difficulties, laryngeal edema, shock and so on, even life-threatening. Patients should immediately inform the doctor, and stop the infusion, oxygen, to maintain a clear airway; 4, drug extravasation: in the process of infusion, if the hand activities lead to intravenous drip needle slipping, will break the blood vessels caused by liquid extravasation, causing the symptoms of hand swelling, usually accompanied by pain. The nurse needs to be informed promptly to stop the infusion and re-puncture. The swollen area can be treated by applying cold compresses to promote vasoconstriction, and then applying hot compresses to help the fluid to be absorbed quickly, which will help to eliminate the swelling.