Excluding special exceptions, in general, for patients with mid-stage gastric cancer, the following points should be noted if they want to improve their prognosis to the greatest extent: 1. Correct diagnosis and reasonable plan: What is correct diagnosis? It means accurate characterization and accurate staging. The tumor in the stomach needs to be very clear whether it is adenocarcinoma or other types of tumors, which is of course the most basic issue, but there are just wrong diagnoses. There are various reasons for the error, relatively common is that the mass found by gastroscopy and the biopsy pathology suggests poorly differentiated cancer, which is most likely to be hypofractionated adenocarcinoma or indolent cell carcinoma, but there is also the possibility of lymphoma, if we do not do further immunohistochemical differentiation and take it for granted that it is gastric cancer and treat it according to the principles of gastric cancer treatment, then we will make a mistake. Accurate staging is also important, even if the qualitative diagnosis is correct, it is gastric cancer. Next, accurate staging examination is needed to clarify which stage it is in. Different staging results in different treatment plans. Early stage is direct surgery, while late stage is not considered surgery, but mainly medication. Then, most of the treatment in the middle stage is direct surgery. However, some patients with mid-stage gastric cancer have obvious local progression of tumor, invasion of surrounding organs or enlarged and fused lymph nodes, so they may need chemotherapy first and then surgery after the tumor shrinks. However, if the staging is wrong and advanced gastric cancer, diagnosed as early to middle stage, is operated directly, then there is little benefit, increasing trauma and treatment cost. However, if the cancer is diagnosed in the middle or even early middle stage, but not given surgery, then it will be more serious, and the gastric cancer which has a chance to be cured will be treated as late stage, and the chance to be cured will be lost. 2.Professional surgery and standard chemotherapy plan: Stomach cancer surgery, like other malignant tumor surgery, requires professional training and a blend of principle and flexibility. Sometimes it also requires a certain spirit of risk-taking and courage, not casual risk-taking of course, but a certain risk-taking based on professional judgment and trust in one’s own surgical ability. Cancer surgery is completely different from surgery for benign diseases, and it is not as simple as removing the stomach or intestines. It is the need for standardized and thorough lymph node dissection to maximize the radical degree of surgery. Taking gastric cancer as an example, mid-stage gastric cancer is required to make the appropriate scope of D2 lymph node dissection according to the specific location of the tumor in the stomach. High-quality radical cancer surgery requires solid professional theories and excellent surgical techniques to ensure. If the degree of professionalism is not enough, if one is not clear about what kind of surgery one wants to do and to what extent is appropriate, maybe confused and done, following the gourd, not knowing why to do so, all surgeries are a pattern and will not have changes according to the actual situation, and ultimately patients’ interests are not basically guaranteed. If the surgical technique is not up to par, then even if the professional theory is good, but when it comes to complex surgery, they don’t know how to start, afraid of heavy bleeding, afraid of accidental closing, then they will be afraid in the surgery, and what can do good radical surgery is made into general or even low quality surgery, and what can be surgically removed is given up surgery because of various reasons. Although both are stomach or intestinal cancer surgery, in fact, the difference between different doctors’ surgery and operation is not one meter or two meters away, it is a qualitative difference. Besides, the standard of chemotherapy regimen, for mid-stage gastric cancer, whether it is preoperative neoadjuvant chemotherapy or postoperative adjuvant chemotherapy. The first-line chemotherapy regimen is oxaliplatin combined with oral fluorouracil (capecitabine or Tegeo). Of course, many doctors will choose other regimens, and it is recommended that the first-line regimen be chosen based on research findings and guideline recommendations. There is also the issue of timing of chemotherapy. Preoperative neoadjuvant chemotherapy is recommended for no more than 4 cycles to prevent excessively long preoperative chemotherapy from increasing the risk of distant tumor metastasis. The overall perioperative chemotherapy duration is preferably not less than six months, with at least 6-8 cycles of 3-week regimen chemotherapy. In addition to the chemotherapy cycle, the chemotherapy effect is also related to the drug dose, and it is best to calculate the standard dose based on the body surface area. The chemotherapy dose cannot be easily or casually changed. 3, after surgery to do regular review, to maintain a healthy state of mind This is a very important issue. Many people do not pay attention to it, thinking that as long as the surgery and or chemotherapy is done, the treatment is complete and it is not important to review or not. In fact, it is a wrong understanding. Post-operative review is very important, can be early detection of abnormal problems, improve the intervention, early treatment, treatment effect is good, can maximize the extension of life, if not timely review, once found very serious problems, often helpless. It is important to maintain a good state of mind, as adults, need to learn to self-adjust, try to maintain a good state of mind, exercise, improve their own immune system, even more effective than considered to take drugs to increase immunity.