There are many factors that lead to the peeling of the skin in the toe cracks, which may be caused by physiological factors such as more sweating of the feet, or pimple scaly tinea pedis, psoriasis, etc., which can be improved by taking general measures, topical medications, oral medications and other measures. 1. Physiological factors: patients with sweaty feet are prone to peeling, so they can choose to replace insoles regularly, air shoes regularly to keep the inside of the shoes dry, or use insoles to inhibit foot odor. 2. Pimple scaly tinea pedis: If tinea pedis causes the toe seam to peel off, you can choose to apply medication externally to the affected area, such as boric acid solution, compound benzoic acid ointment, miconazole nitrate, as well as terbinafine cream and other antifungal medication. More serious symptoms require systematic drug treatment, you can choose oral itraconazole or terbinafine. 3. Psoriasis: Psoriasis involving the toes can also lead to peeling of the toes, you can choose to use topical retinoic acid, carbotriol cream, tacrolimus cream and other treatment. Peeling toes need to be treated according to the specific cause, it is recommended that patients go to the dermatology department in a timely manner to seek professional medical help, avoid self-medication, so as not to delay the condition.