The difference between a positive and negative urine test is the presence or absence of abnormalities in the urine test items. If there is an abnormality, it is positive. If all the items in the urine test are negative, it suggests normal. The presence of a positive test indicates that there is some problem in the urine, which needs to be specifically analyzed to determine which problem it is and treated with the necessary pharmacological interventions, or further ancillary tests are needed. If the urine test is completely negative, there is no need for any tests or treatment. When there is a positive result, symptomatic treatment is needed depending on the specific item of the positive result. If the urine is positive for red blood cells, a bleeding disorder should be considered and further ultrasound examinations are needed to rule out stones, tumors and other diseases. If there is a positive result for white blood cells, then an infection should be considered and further urine culture tests need to be taken to find out if there is an infection.