Nausea and vomiting in a 45-year-old woman may be caused by physiological factors such as diet, or due to digestive system, nervous system and other diseases. 1. Physiological factors: some bad eating habits, such as overeating, eating too fast, or eating too much cold, spicy and other stimulating food and fried and other indigestible food, will increase the gastrointestinal digestive burden, may cause nausea and vomiting. In addition, 45-year-old women may also be due to menopause, due to the decline in ovarian function caused by changes in the level of hormones in the body, thus affecting the gastrointestinal function, so that the patient appeared bloating, loss of appetite, nausea and vomiting, indigestion and other gastrointestinal symptoms. 2. Digestive system diseases: if the patient suffers from gastroenteritis, peptic ulcer, gastrointestinal dysfunction, dyspepsia, hepatitis, cholecystitis and other diseases, it will make the gastrointestinal digestive and absorption function weakened, resulting in nausea and vomiting symptoms. 3. Neurological diseases: diseases such as intracranial tumors and other intracranial space-occupying lesions causing increased intracranial pressure, or Meniere’s syndrome, vestibular neuritis and other peripheral nervous system lesions, may cause nausea and vomiting. If a 45-year-old woman still has menstrual flow, it is not excluded that the nausea and vomiting is caused by early pregnancy reaction. When 45-year-old woman nausea, it is recommended to seek medical attention, identify the cause of the disease, targeted treatment, so as not to delay the condition.