There are three internationally recognized endpoints for the treatment of chronic hepatitis B. The conversion of hepatitis B virus during treatment is the most basic endpoint, and obtaining this result requires continued treatment and is not a criterion for drug discontinuation, which is very prone to relapse. For HBeAg-positive patients, achieving durable e antigen serological conversion after drug discontinuation, that is, achieving the disappearance of E antigen with the emergence of E antibody is a satisfactory treatment endpoint, and achieving this goal means that the body’s immunity to slow hepatitis B is restored and the drug can be safely discontinued for a long time. Its risk of liver cancer and cirrhosis is greatly reduced. The ideal therapeutic endpoint is to achieve durable disappearance of surface antigen after drug discontinuation, i.e. “clinical cure”. Achieving a “clinical cure” means that the patient has removed the “cap” of chronic hepatitis B. The incidence of hepatocellular carcinoma decreases and the patient is basically as healthy as a healthy person, and his or her quality of life is greatly improved. “The aim is to suppress the virus to reach the most basic endpoint, and a few patients can reach the ideal endpoint. However, this treatment requires long-term medication, which is difficult for some patients to adhere to, and is prone to relapse once the medication is discontinued. In contrast, interferon is more advantageous for achieving durable e antigen serological conversion in terms of satisfactory endpoint attainment. In addition, in daily life, we must pay attention to the maintenance of the liver, to protect the liver, abstain from alcohol is the first, while maintaining adequate sleep; liver is the largest digestive gland in the digestive system, the role of diet on the liver is also very important, adjust their own eating habits, to eight full and balanced diet, for processed food, fried food, half raw or burnt food should not be too much intake, do not Do not overeat or skip breakfast, do not take long-term painkillers and other drugs to increase the burden of liver detoxification.