Silymarin is able to lower aminotransferases, but it is not applicable to all causes of elevated aminotransferases. Silymarin has the effect of stabilizing the liver cell membrane, in addition, it can also protect the liver enzyme system, improve the detoxification ability of the liver, applicable to acute and chronic hepatitis, such as viral hepatitis, alcoholic hepatitis, drug hepatitis and other causes of hepatic impairment, can also be used for fatty liver caused by liver dysfunction, can effectively alleviate the transaminase elevation caused by such diseases. However, it should be noted that for patients with autoimmune hepatitis and other diseases, taking silymarin can not play a role in reducing transaminases. Such patients are usually due to abnormal immune function caused by the disease, can be prescribed to use prednisone and other hormone drugs for treatment. Adverse effects of silymarin mainly include nausea, vomiting, etc. In addition, the contraindications for the use of the drug have not yet been clarified, so the use of the drug must be carried out under the guidance of a medical professional.