Whether high total bilirubin and indirect bilirubin is important or not depends on the cause of elevation and the degree of elevation of plasma bilirubin. Generally speaking, if the elevation is caused by physiological reasons and the degree of elevation is not obvious, it is not important and should be found out under the guidance of the doctor. Elevated total bilirubin and indirect bilirubin can be categorized into physiological and pathological elevation. Physiological elevation means that the total bilirubin and direct bilirubin are not elevated to a large extent, other indexes are normal, and there is no discomfort in the body, e.g., physiological jaundice in newborn babies, etc., which can generally subside on its own, and it is not serious, and a good living habit should be maintained. Pathological elevation, usually caused by liver disease, indicates that the liver cells are damaged, and the cause of the disease should be identified in time. If the elevation is not obvious, it means that the degree is relatively mild and can be better treated. When the degree of elevation is too large, exceeding the normal 2~3 times, it indicates that the liver is damaged, and should be taken seriously and seek medical treatment in time. Should maintain a good habit of life, for the protection of the liver is very useful, and liver disease is generally not obvious early symptoms, should pay attention to the physical examination, and when the body does not feel well in time to consult a doctor, so as not to delay the condition.