After relapse of acute myeloid leukemia with re-induction chemotherapy, remission is usually still possible, but the remission rate is relatively low. After relapse, chemotherapy and hematopoietic stem cell transplantation can be chosen for treatment. 1. Chemotherapy: High-dose cytarabine or azacitidine combined with vinblastine can be chosen as the chemotherapy regimen for patients with acute myeloid leukemia. 2. Hematopoietic stem cell transplantation: For relapsed AML patients, hematopoietic stem cell transplantation is also an option after chemotherapy remission. If complete remission is not achieved after re-induction chemotherapy, salvage transplantation can be performed if the immune residue is positive, but the risk is higher. Acute myeloid leukemia relapse. Patients should be followed up regularly for review and should be detected and treated early once there is a tendency to relapse.