Failure of wound healing after surgery may be caused by wound infection, slow repair of traumatized tissues or hypoproteinemia, and medication such as mupirocin ointment and recombinant human epidermal growth factor should be used according to the different causes of the disease. 1. Wound infection: The wound will not heal due to the invasion of microorganisms from the wound wound wound, resulting in an inflammatory reaction. Usually, you can use hydrogen peroxide to clean the wound under the guidance of the doctor, and then apply mupirocin ointment on the affected area to fight infection, and at the same time, you can take amoxicillin capsules to eliminate inflammation. 2. Slow repair of traumatized tissue: patients due to burns, pressure wounds and a series of factors lead to the wound near the epithelial cells can not proliferate quickly, affecting wound healing. You can apply topical recombinant human epidermal growth factor on the wound under the doctor’s advice to accelerate the proliferation of epithelial cells near the wound and speed up the wound healing. 3. Hypoproteinemia: The protein in the blood is lower than the normal level due to untimely protein supplementation after surgery, which affects wound healing. Under medical advice, intravenous injection of albumin and other nutrients can be given to meet the nutrient content needed for wound healing and promote wound healing. For patients whose wounds fail to heal after surgery, the cause of the disease should be promptly identified and treated as soon as possible.