If the acne on the nose turns into a fleshy ball, it is possible that the original inflammatory acne has aggravated and formed a relatively large abscess. At this time, anti-infection treatment is needed. Topical fusidic acid cream or mupirocin cream can be applied topically. If necessary, oral antibiotics are needed, usually minocycline or doxycycline, and also Chinese medicines such as Niuhuang Shangqing Capsules or Gentian Liver Pills. Of course, while these medications, try to keep the local cleanliness and hygiene to prevent the expansion of infection.