Nipple cancer refers to breast cancer that occurs in the nipple area, such as eczema-like breast cancer, and its surgical scope needs to be decided according to the tumor stage. However, it is usually difficult to achieve the treatment by only removing the nipple. Eczema-like breast cancer is a type of breast cancer characterized by skin eczema. This type of breast cancer has low malignant degree, slow progression of disease and late lymphatic metastasis. Clinical manifestation is itching and burning sensation on unilateral nipple, areola and its surrounding, presenting red patchy eczema-like appearance with clear boundary, with oozing crust or keratinized flaking on the surface, and ulcers can be formed in serious cases. Surgery should be chosen for the modified radical mastectomy of breast cancer; and malignant tumors are also prone to recurrence and metastasis after surgery, and after surgery, it is also necessary to combine the detailed pathological types and metastasis of lymph nodes with the choice of auxiliary treatment plan and regular review. It is suggested that breast cancer patients should consult regular hospitals in time and take reasonable treatment under the guidance of doctors, so as to curb the progress of the disease and avoid aggravation of the condition.