There are five major categories of antihypertensive drugs that can be taken for a long time, also known as first-line antihypertensive drugs, these drugs: 1, beta-blockers, commonly used drugs are metoprolol tartrate, metoprolol succinate, bisoprolol tablets, metoprolol tablets, these drugs are commonly used clinically betalactone, etc. 2, calcium antagonists, such as nifedipine extended-release tablets, felodipine tablets, commonly used drugs are luohuaxi, baixin with, etc. 3, angiotensin receptor antagonists, commonly used drugs are captopril, perindopril, etc. 4, angiotensin receptor antagonists, commonly used drugs are valsartan, timetan, candesartan, etc. The most common drugs used are captopril, perindopril, etc. 4, angiotensin receptor antagonists, commonly used drugs are valsartan, telmisartan, candesartan, etc. 5, diuretics, commonly used drugs are furosemide, hydrochlorothiazide, dihydrochlorothiazide tablets. These drugs can be taken for a long time, but when taking them, you need to regularly monitor liver function, kidney function, blood ions and so on.