Acetaminophen does not cause sleepiness, and the adverse effects of acetaminophen in normal doses are relatively rare, and may occasionally cause patients to have nausea, vomiting, sweating, abdominal pain, and pale skin. In a small number of cases, allergic problems may occur, causing patients to have a rash, or causing patients to have thrombocytopenia, granulocyte deficiency, leading to gastrointestinal bleeding, but mainly seen in patients with gastric ulcers. Acetaminophen clinical safety is relatively high, acetaminophen in the clinical mainly have antipyretic and analgesic effect, can be used for colds, fever or arthralgia, neuralgia, migraine treatment, but also can be used for post-surgical pain relief. Its antipyretic effect is similar to that of aspirin, but its analgesic effect is weaker than that of other analgesics.