Breast BI-RADS (Breast imaging reporting and data system) grading is the standard used to indicate breast changes in the Breast Imaging Reporting and Data System (BI-RADS), created and recommended by the American College of Radiology (ACR). The BI-RADS grading is as follows: Grade 0: Needs to be recalled and re-evaluated in conjunction with other exams, indicating that the information obtained from the exam may not be complete. Grade I: No abnormality is seen. Grade II: benign changes are considered and regular follow-up is recommended (e.g., once a year). Grade III: Benign disease is possible, but a shorter follow-up period (e.g., once every 3-6 months) is needed, and the percentage of malignancy at this level is less than 2%. Grade IV: malignant lesion is considered possible and requires biopsy for clarification. Grade V: Highly suspicious of malignant lesions (almost identified as malignant disease), requiring surgical excisional biopsy. Grade VI: Malignant lesion has been confirmed by pathology. When you get the report as how many grades of breast alteration BI-RADS, don’t be nervous first, don’t think that the report BI-RADS so-called grade I and II is the stage I and II of breast cancer. In fact, only grade III onwards needs to be treated with caution. Of course, the degree of breast disease cannot be judged from imaging data alone, but clinicians need to make a comprehensive analysis by combining medical history, physical examination, laboratory tests and other information before giving treatment recommendations.