In daily life, many patients have encountered misdiagnosis. The causes of misdiagnosis are very complex. The misdiagnosis of a patient involves many factors such as the physician, the patient, the disease itself, hospital equipment conditions and society. It is true that it is crucial for the doctor to identify the cause of the disease in a timely and accurate manner and to give reasonable treatment to the patient. However, misdiagnosis can be reduced if the patient actively cooperates with the doctor. Some clinical misdiagnosis is indeed caused by the patient’s own subjective factors, which often affect the authenticity of the history, signs and test results, thus seriously interfering with the doctor’s thinking and understanding, leading to misdiagnosis. The reasons for common misdiagnosis on the part of the patient are roughly the following: concealment of medical history: some patients have unspeakable privacy and are reluctant to reveal their truth to the doctor for fear of affecting their reputation. Exaggerating the condition: Many patients are afraid of not getting sympathy from the doctor when they visit the doctor and exaggerate their condition when they tell their medical history, which leads the doctor’s attention and judgment in the wrong direction. Some elderly hypertensive patients are originally mild genus one, because of exaggerated self-perceived symptoms, and doctors ignore a comprehensive multi-organ examination, misdiagnosed as severe, inappropriate additional antihypertensive drugs, resulting in the induction of angina and stroke. Lack of cooperation: I often encounter a small number of patients lacking cooperation when I see them, they tell a rambling, disorganized medical history, often deviating from the doctor’s guiding questioning, answering the wrong questions. Inadequate history taking, especially in busy outpatient clinics, and lack of cooperation during physical examinations can also lead to misdiagnosis. Blindly seeking medical treatment: With the continuous development of medical science, clinical subspecialties are becoming more and more detailed. While this is beneficial to the in-depth study of each specialty, it also brings inconvenience to patients seeking medical care. For example, a patient with glaucoma consulted internal medicine for headache, nausea and vomiting, and was diagnosed with “gastrointestinal flu”, but treatment was ineffective.