Epidemic diarrhea of newborn (epidemicdiarrheaofnewborn) is an outbreak of epidemic diarrhea health search in the maternity ward or hospital neonatal ward health search due to the imperfect immune function of newborns and environmental factors, prone to infection health search pathogens to bacteria, viruses, fungi parasites are more common mainly through the maternal birth canal is contaminated with milk water, nipples The main cause of epidemic infection in newborns is the mother’s birth canal. What causes neonatal epidemic diarrhea? Many bacteria and viruses can cause epidemic diarrhea in newborns. For example, ① Escherichia coli is most common as pathogenic Escherichia coli (EPEC). ②Salmonella typhimurium caused outbreaks of epidemic diarrhea occurred several times in some areas of China in the 1980s, and the disease was quite serious, but there were also very mild small epidemics caused by Salmonella agalactiae. ③ Other bacteria such as Campylobacter jejuni, Pseudomonas aeruginosa and Aspergillus can cause diarrhea in newborns, but rarely cause pandemics. ④Rotovirus is the most common agent in viral diarrhea and can cause epidemic diarrhea in neonates. There are also rotavirus-like factors such as micro rotavirus that can occasionally cause epidemic diarrhea. Others such as coronavirus, coxsackie B virus, and echovirus can cause diarrhea but have not caused epidemics. Prevention of neonatal epidemic diarrhea focuses on disinfection and isolation and treatment of the patient to cut off the source of infection. If an epidemic is found to be unavoidable, infants who have been in direct or indirect contact should be immediately grouped together in a ward and closely monitored for the occurrence of diarrhea by daily stool cultures. Those with positive stool cultures are then isolated in a separate room. Some authors believe that all those with positive stool cultures should be given a 5-day course of antibiotic prophylaxis with or without diarrhea, but some oppose drug prophylaxis because the rate of carriage of bacteria is higher after drug prophylaxis and symptoms may be delayed, and sometimes symptoms may recur, prolonging the epidemic.