IgA nephropathy is a primary glomerular disease characterized by the deposition of IgA particles in the glomerular mesangial area, with hematuria, proteinuria of different degrees as clinical manifestations, and the staging is commonly used in Lee’s classification, which is divided into five stages. Stage I: the vast majority of glomeruli are normal, with occasional mild thylakoid widening and staged hyperplasia, with or without cell proliferation, and no tubulointerstitial lesions. Stage II: focal glomerular thylakoid proliferation and sclerotic lesions, glomerular number less than 50%, rare crescents, no tubulointerstitial lesions. Stage III: Diffuse thylakoid proliferation and widening, occasional focal stage with small crescents, adhesions, tubulointerstitial lesions with focal interstitial edema, occasional cellular infiltration, rare tubular atrophy. Stage IV: severe diffuse thylakoid proliferation and sclerosis, partial or total glomerulosclerosis, crescents less than 40%, tubular atrophy, renal interstitial infiltration, occasional interstitial foam cells. Stage V: glomerular and tubulointerstitial lesions similar to stage IV, but more serious, glomerular crescent formation is greater than 45%. Patients with IgA nephropathy should go to the hospital in time for consultation and active treatment under the guidance of professional physicians.