Anal atresia is a congenital malformation, which can be diagnosed when no anal structure can be found in the normal position of the anal opening after the child is born. The general clinical manifestations are mainly the absence of normal fetal bowel movement and the inability to find anal structures at the anal opening, accompanied by clinical manifestations such as abdominal distension, nausea and vomiting, which make the diagnosis clear. According to the place of the anal opening, the height from the atretic end of the cecum is not the same can be diagnosed as low anoikis, middle anoikis and high anoikis, generally speaking, low anoikis surgery will be better, high anoikis effect will be worse. There is only one way to treat this lesion, and that is with early surgery. Surgery is the only way to resolve anoikis and to form a normal anus for normal defecation. Congenital anencephaly is a congenital malformation with a relative incidence of about 1/3000, with a higher incidence in boys than in girls, and the main treatment is timely surgery.