At 35 years old, the age is still a youth, but the body is …… solid. The youth referred to in the Medium and Long Term Youth Development Plan (2016-2025), issued and implemented by the Central Committee of the Communist Party of China and the State Council on April 13, 2017, is 14-35 years old. However, different organizations around the world have different segments of youth age, please see the following set of data, welcome to the number: World Health Organization (2013): under 44 years old UNESCO: 16-45 years old National Bureau of Statistics of China: 15-34 years old Communist Youth League of China: 14-28 years old Youth Federation of Hong Kong, Macao and Taiwan: 10-24 years old Are you grasping the youth’s Have you caught the tail end of your youth? Let’s take a look at the medical and sociological divisions of age: the optimal age for women to give birth is considered to be 25 to 29 years old for women and 25 to 35 years old for men. Mothers over 35 years of age, or 34 years of age at the time of conception, are referred to as “senior mothers”. 35 years of age is still a young age, but the body …… is heartbreaking. Women’s Age and Fertility For women, the age of 35 is indeed a watershed moment. The most obvious is that as age increases, the number and quality of eggs decline, and it is difficult to get pregnant and the incidence of complications during pregnancy increases. Specifically manifested in: 1, fertility decline Normal couples have a 20-25% chance of conception per ovulatory cycle, and the chance of conception without contraception for 1 year is 58%, and for 2 years is 93%. According to the Infertility Guidelines published by the British Human Reproduction and Embryology Authority, the fertility of women at the age of 35 is only 50% of that at the age of 25, and drops to 50% of that at the age of 35 by the age of 40. 2, increased risk of genetic diseases in offspring Increased risk of Down’s syndrome and other genetic defects, in terms of Down’s syndrome (21 – trisomy), the mother’s age of 20 to 29 years old, the chances of conceiving a Down’s child is about 1/1667, 30 to 39 years old rose to 1/952, 40 to 49 years old rose significantly to 1/106, to the age of 49 years old and above, the risk of up to 1/11, every 11 people have one! 3, increased risk of complications during pregnancy Many women of advanced maternal age may have mild diabetes or hypertension, usually normal body functions, did not realize. Once pregnant, the body’s functions and hormone level changes will induce these hidden diseases, not only affect the normal development of the fetus, but also bring life-threatening to pregnant women. The risk of miscarriage also rises from 12% at age 30-34 to 18% at age 35-39. First-time mothers over 35 have a 40% risk of miscarriage and an increased risk of gestational hypertension syndrome, anemia, gestational diabetes, weak contractions, postpartum hemorrhage and intrauterine growth retardation, and preterm delivery during pregnancy. Women over the age of 40 have only about 5% chance of getting pregnant. Common problems include blocked fallopian tubes and thin uterine lining in addition to deterioration of ovarian function, so preparation for pregnancy at an advanced age faces more difficulties than general preparation for pregnancy. Male Age and Fertility 1, Sperm Quality Decline As men age, the incidence of mutation or aneuploidy increases, sperm quality (vitality) decreases, the conception rate decreases, the miscarriage rate increases, and the number of birth defects increases. the fertility of men over 40 years of age decreases significantly. Analysis and review of clinical data on sperm quality and seminal plasma biochemistry (seminal plasma elastase sclerostinase, seminal plasma neutral α-glucosidase) of 3262 patients tested in outpatient clinics of Jiaxing Maternal and Child Health Hospital showed that: the prevalence of reproductive tract infections in male outpatients; with increasing age, the incidence of plasma elastase sclerostinase abnormality and the value of seminal plasma elastase sclerostinase measurements have an increasing The tendency is to increase with age; oligospermia, oligozoospermia and hypospermia, which are accompanied by reproductive tract infections that are difficult to self-cure, may be related to the increase in the age of male patients. 2.Single gene genetic disease The risk posed by the mother’s advanced age is mainly the risk of carrying a fetus with non-integer chromosomes, most of which are eliminated naturally in the early stages of pregnancy, and only individual abnormal fetuses such as trisomy 21 and trisomy 18 can survive. And new research proves that if the father is of advanced age (over 46 years old), the risk of the child developing a single-gene genetic disease is increased. Most of the monogenic diseases are rare diseases, and some of the rare diseases are facing the dilemma of “lack of medical treatment and lack of medication”. 3, mental illness In fact, whether using assisted reproduction or natural fertilization, elderly men’s sperm mutation and decline in sperm count will reduce the chances of successful fertilization. Studies have also shown that older men are more likely to have genetic errors in their sperm, which has been implicated in the development of autism and schizophrenia in children. Older men are more likely to have “nasty” offspring, and child health is strongly correlated with the age of the father at the time of birth. However, women’s age still has a higher impact on fertility than men’s age. How should I prepare for pregnancy if I am over 35? 1, pre-pregnancy checkups, husband and wife checkups Marriage checkups, pregnancy checkups and maternity checkups are important means to ensure eugenics, to understand the physical condition of women preparing for pregnancy, and to provide guidance for scientific preparation for pregnancy. And pregnancy test is more important for older pregnant women, for example, ultrasound can check the uterus, ovaries have no anomalies; reproductive system check to rule out the presence of inflammation, tumors and other organic lesions, are to ensure the best state of conception. 2, husband and wife supplement folic acid The importance of folic acid has been mentioned many times, and will not repeat here. Secondly, men should reasonably supplement minerals. Calcium, zinc, selenium, copper, sodium, etc. can affect the quality of sperm and have a close relationship with the improvement of sperm vitality. 3, change the bad habits Stay up late Men often stay up late will make the sperm quality decline significantly. Especially after men reach the age of 35, the integrity of sperm DNA deteriorates, easily leading to chromosomal aberrations. Women who stay up late for a long time will also affect the quality of eggs, and men and women who are preparing for pregnancy should pay attention to the regularity of work and rest. Long-term smoking and alcohol Long-term smoking and alcohol will also increase the rate of fetal malformation, affecting the development of the embryo, so to have a healthy baby, must be at least six months in advance to do a good job of quitting smoking and quitting the preparation. 4, a healthy diet, reasonable intake of nutrients before pregnancy need to consume more vegetables containing vitamins, high fiber, etc., older pregnant women can increase calcium-containing food supplements, such as dairy products. As older women with high blood pressure during pregnancy, the chances of diabetes increase, daily nutrition should be reasonable, avoid over-nutrition. To limit high sugar, high fat food; fruit intake should also be moderate, not the more the better. 5, exercise Whether it is a man or a woman, three months to six months before the pregnancy, we should start to strengthen the exercise, improve physical fitness, ready for the baby. During the preparation for pregnancy at an advanced age, exercise is also essential, appropriate, regular physical exercise can not only promote the reasonable deployment of hormones in the female body, but also to avoid miscarriage in early pregnancy. 6, maintain a relaxed mood This is the most important, but also the most easily overlooked point, the mood is very important, the more anxious, the more you think about conceiving, the less likely to succeed. Never take it seriously, but it is a natural law, how many people have come over. So don’t put too much pressure on yourself, just go with the flow.