Osteoarthritis of the knee is a degenerative joint disease caused by aging and other factors such as obesity and injury, resulting in abnormalities in the biochemical metabolism of articular cartilage and loss of proteoglycans, leading to localized softening, wear and tear, and structural destruction of articular cartilage, which may be accompanied by secondary osteophytes, eventually leading to joint pain and even loss of function. Clinical symptoms such as knee pain, restricted movement and joint deformity can occur. Pain occurs with activity, so middle-aged and elderly people experience pain when walking up and down stairs, walking with weight, and walking long distances, which may gradually resolve after rest. Among the causes of osteoarthritis, age is the most dangerous factor. osteoarthritis is rare before the age of 40, but after the age of 50, the incidence of the disease increases exponentially, and the prevalence of radiologically diagnosed osteoarthritis in people over 60 years old is 42% in China. This is followed by weight, with knee osteoarthritis occurring in 60% of overweight individuals over the age of 65. Thus, knee osteoarthritis is the most common cause of activity in the elderly. The first step in the process of choosing a treatment plan is for the physician to do a good job of patient education and counseling. The physician should reassure the patient that most patients with osteoarthritis, who are able to carry on a normal life, can reduce symptoms and improve function by taking a series of simple, effective measures such as rest and exercise, pain medications, physical therapy and weight loss. Patients should be encouraged to change their lifestyle and exercise patterns and avoid inappropriate activities that can aggravate joint degeneration. Secondly, better cooperation from the patient is needed, especially in weight reduction and functional rehabilitation, and only with full cooperation from the patient can the treatment be achieved. Third, the doctor should fully understand the advantages and disadvantages of various treatments and explain to the patient the precautions to be taken during the treatment. For example, the application of pain medication should be proportional, as excessive application can cause excessive knee movement and aggravate joint degeneration, as well as the risk of causing peptic ulcers. Intra-articular injection of hormones may cause infection, overuse of the joint, resulting in imbalance of cartilage nutrition and hormone tiny crystals have an abrasive effect on cartilage, the number of injections should not exceed 3 times in a year.