Clinical anemia in diabetic patients is often manifested as fatigue, pallor, and some patients have panic attacks and chest tightness. Clinical treatment needs to be carried out according to the type of anemia and the severity of the patient’s condition, mainly in the following cases: 1, according to the patient’s type of anemia to be given supplementation with different nutrients, such as iron-deficiency anemia needs to be given supplementation with iron; megaloblastic anemia, which needs to be given supplementation with vitamin B12 and 2, need to actively search for the cause of anemia, iron deficiency anemia is mostly seen in chronic blood loss; women mostly due to uterine fibroids caused by excessive menstruation and anemia; diabetic patients need to pay attention to exclude digestive diseases caused by chronic blood loss, need to improve the gastroscopy colonoscopy. 3, if the patient’s degree of anemia is more serious, such as blood pigment is less than 6g/L, while the patient is accompanied by symptoms such as panic, fatigue and other symptoms, need to be given red blood cell transfusion to correct anemia, and need to be given to the patient. Red blood cell transfusion should be given to correct the anemia and reduce the patient’s symptoms.