There is generally no most effective way to treat a baby’s nighttime cough. Coughing at night may be related to upper respiratory tract infections, cough variant asthma and other diseases, need to clarify the cause of the disease, to take general treatment, medication and so on. 1. Upper respiratory tract infection: baby cough at night may be related to upper respiratory tract infection, it is recommended to pay attention to warmth during sleep, avoid cold, indoor temperature and humidity to maintain a certain degree, drink more water and so on. If not relieved, you can take pediatric cold granules and other treatments, accompanied by bacterial infection also need to take amoxicillin and other antibiotic treatment. 2. Cough variant asthma: Cough variant asthma is mostly related to genetic or environmental stimuli, can also be manifested as night cough, but mainly dry cough, can use budesonide, fluticasone propionate and other hormones to relieve, but also with the use of albuterol and other drugs. Usually pay attention to maintain indoor hygiene and cleanliness, avoid contact with allergens and so on. There may be other reasons for your baby’s nighttime cough, so we recommend that you go to a regular hospital in time to avoid delaying your condition. The use of medication should follow the doctor’s instructions.