Menstruation has not been, showing a thick lining, taking progesterone has been blood, to rule out pregnancy can be considered after the diagnostic scraping treatment. Delayed menstruation should first rule out pregnancy. Taking progesterone without pregnancy but with a thick lining can cause the lining to shift to the secretory phase, and menstruation will occur after the medication is stopped. If vaginal bleeding occurs while taking progesterone, you can consider doing a diagnostic curettage to stop the bleeding and at the same time take the endothelium for pathological examination to determine whether there is any abnormal proliferative lesion, and then proceed to further treatment. In the next menstrual period can also be carried out sex hormones, thyroid function, ultrasound and other auxiliary examination to clarify the cause of irregular menstruation or endometrial thickening. Specific medication regimens should be administered under the direction of a physician.