Taking high blood pressure medication and having a blood pressure of 158mmHg is generally more serious. If the blood pressure of hypertensive patients still does not fall after taking antihypertensive drugs, it means that the current blood pressure control is not up to the standard, and it is necessary to continue to monitor, and at the same time, it is necessary to make clear that there is an erroneous omission of medication, whether it is combined with an irregular life, dietary intake of excessive salt, whether it is combined with insomnia, sleep apnea and so on, whether it is combined with the application of drugs affecting blood pressure, and adjust the type of medication and the dosage under the guidance of the doctor when necessary,. It may also be caused by secondary hypertension, such as renal artery stenosis, renal hypertension, obstructive sleep apnea syndrome and so on. It is necessary to clarify the condition and actively treat the primary disease. At present, it is recommended to go to the hospital in time, and cooperate with the doctor to carry out the relevant examination and treatment.