Difficulty in swallowing in gastric impression cell carcinoma suggests that the disease has further progressed and distant metastasis may occur, and chemotherapeutic drugs, targeted therapy and placing jejunal nutritional tube are suggested to alleviate the symptoms. 1. Chemotherapeutic drugs: commonly used chemotherapeutic drugs include 5-fluorouracil, capecitabine, cisplatin and so on, which can kill cancer cells to achieve the therapeutic purpose by using chemotherapeutic drugs. 2. Targeted therapy: Targeted therapy refers to the treatment of cancer-causing sites that have been clearly identified at the cellular molecular level. Commonly used drugs include Trastuzumab and Apatinib. 3. Insertion of jejunal nutrient tube: jejunal nutrient tube insertion can be chosen to input nutrient liquid into the body to relieve malnutrition caused by dysphagia. In addition, it is suggested that patients with gastric impression cell carcinoma who have dysphagia should go to hospital timely and follow the doctor’s instruction for treatment to avoid delaying the condition.