The process of chronic hepatitis B virus infection is the process of the body’s struggle with the virus and the development of anti-hepatitis B virus immunity, the degree and speed of immune development varies from person to person and the outcome of the disease varies greatly. About 25% of chronic hepatitis B virus carriers develop hepatitis, which is the current existence of hepatitis B patients with varying degrees of severity; about 75% are stable chronic carriers. About 10% of chronic carriers with “major triplet” will naturally convert to “minor triplet” each year; about 5% of chronic carriers with “minor triplet” will naturally clear “minor triplet” each year. Among all chronic carriers, 2-3% of them will naturally clear the virus each year and eventually regain their health. The clearance of chronic carrier status is age and gender dependent: women clear carriers earlier; the younger the carriers, the more stable they are, and the older they are, the more they clear. Infection in children and adolescents has been significantly reduced due to the universal hepatitis B vaccine; currently about 10% of adults are chronic carriers of hepatitis B virus, while less than 5% are over 60 years old, I have only seen a few people over 80 years old so far, and I have never seen a chronic carrier over 90 years old. After long years of carrying the hepatitis B virus, the human body gradually develops specific antiviral immunity and eventually almost always clears the virus, so chronic carriers of hepatitis B are not infected for life.