Allergic patients and their immediate family members with a history of bronchial asthma, hay fever, eczema, or angioneurotic edema, or those who have been injected with horse serum preparations in the past, and patients with a positive tetanus allergy test are prone to be allergic to tetanus injections. Adverse reactions to tetanus injections include anaphylaxis, serum sickness such as urticaria, fever, lymph node enlargement erythema, itching, and edema at the injection site. Tetanus injection is strictly prohibited intravenous injection, is not recommended with other vaccines at the same time, the injection is used immediately after opening, the injection needs to be observed at the scene for at least 30 minutes, no abnormalities before leaving, after returning home, adverse reactions should be promptly seek medical attention. It is recommended to go to a regular hospital under the guidance of a doctor to use, do not use drugs privately to avoid causing adverse effects.