Sleep deprivation can lead to increased blood pressure because prolonged sleep deprivation can lead to the development of metabolic syndrome, such as a mild increase in blood glucose, increased blood lipids, and an increase in uric acid in patients. Obese people often have nocturnal sleep-apnea syndrome, and evidence-based medical research shows that sleep-apnea syndrome can lead to the development of metabolic syndrome. This can include hyperlipidemia, hyperglycemia, hypertension, and hyperhomocysteine, so sleep deprivation can cause elevated blood pressure in patients. In the case of sleep deprivation, the patient’s blood pressure is mainly elevated at both low and high pressure, and may be accompanied by obesity. The first choice of oral medication is calcium antagonists, and it is also necessary to actively adjust sleep and improve sleep quality.