After the gastric ESD surgery, it takes about 10-20 days to recover, if there is no obvious discomfort, you can follow the doctor’s advice to take the medication for the eradication of Helicobacter pylori. Gastric ESD surgery refers to the gastric submucosal peeling surgery, this surgery will produce a certain damage to the gastric mucosa, resulting in local mucosal congestion and edema, and the eradication of Helicobacter pylori amoxicillin, tinidazole and other drugs may produce a certain degree of gastric mucosal irritation, you need to be in the 10-20 days after the operation after the mucous membrane tissues are gradually growing and healing before you can begin to take medication, so that the adverse effects will be relatively small. This way, the adverse effects will be relatively small. After the gastric ESD surgery, if you need to take drugs to eradicate Helicobacter pylori, you must take them correctly under the guidance of a doctor, and also pay attention to dietary patterns, and if the discomfort continues to worsen after taking the drugs, it is recommended that you consult a doctor in a timely manner to check and stop taking the drugs for observation.