Taking progesterone capsules will in most cases not cause weight gain because progesterone capsules are progestins and progestins do not cause water and sodium retention in the body after taking them, so they tend not to cause weight gain. Of course, if you improve your diet while taking progesterone capsules, an increase in appetite may cause weight gain, so diet is the key. In addition, if you take medications containing estrogen in your daily life, it may lead to weight gain, mainly because estrogen causes water and sodium retention in the body, which can cause weight gain and obesity. When taking progesterone capsules: 1. Be sure to take the medication under the guidance of a doctor, otherwise it may delay the condition or lead to menstrual disorders. 2. It is recommended to take it orally before going to bed, because progesterone capsules may cause dizziness after eating, and taking it before going to bed avoids this phenomenon.