The most common gastrointestinal symptom experienced by patients while taking progesterone capsules was causing nausea, and no other gastrointestinal symptoms were seen. Adverse effects of progesterone capsules, including causing breakthrough bleeding, vaginal spotting, weight gain or weight loss in patients, as well as cervical squamocolumnar junction changes, changes in the nature of cervical secretions, breast swelling, dizziness, headache, tiredness, fever, insomnia, allergy, rash with or without pruritus, melasma, chloasma, obstructive jaundice, and abnormal liver function. When using the medicine, you must pay attention to observation, and please consult the doctor promptly for any abnormal performance. Progesterone capsules should be prohibited for the following diseases, such as unexplained vaginal bleeding, thrombophlebitis, vascular embolism, stroke or previous history of cerebral embolism, breast tumor, genital tumor.