In recent years, the serious complications of cardiovascular and cerebrovascular diseases caused by “three highs”, such as coronary heart disease, cerebral infarction, diabetes, kidney disease, etc., have been recognized by the majority of medical workers and the general public, but the leg vascular complications caused by “three highs”, lower limb The arteriosclerotic occlusive disease of the lower extremities caused by the “three highs” has not been widely appreciated. In comparison, people are relatively familiar with the arterial complications of the lower extremities caused by diabetes, but very little is known about the arterial diseases of the lower extremities caused by hypertension and hyperlipidemia. However, it is not that there are fewer patients, but they are neglected. These leg blood vessels are as terrible as cardiovascular disease. If the “three highs” are not treated well for a long time, complications of large blood vessels can occur, mainly early or accelerated development of atherosclerosis. Atherosclerosis does not only occur in the coronary arteries, it can occur in any artery, and it is not uncommon for it to occur in the arteries of the lower extremities. If the arteries in the lower extremities are narrowed or occluded, there will be cold legs, fear of cold, numbness, weakness, inability to walk long distances or even pain, etc. In severe cases, this can lead to foot ulcers or gangrene of the toes. It takes 10-20 years to go from mild stenosis to 50% blockage, during which time the patient has no symptoms or mild symptoms, and only feels cold, weak, and unable to walk far. Once there is a significant intermittent claudication, i.e., sore legs after walking a short distance and needing to sit down and rest for a while before continuing to walk, it means that the blood supply to the legs has become significantly insufficient under active conditions. If this period is not diagnosed and treated, the condition further develops to the point where the leg feels pain even when inactive, and even blackened necrosis of the toes occurs, it means that the arteries of the lower limbs are severely narrowed or even occluded, and some patients have to have their limbs amputated as a result. Therefore, “three high” patients should pay attention to the emergence of cardiovascular and cerebrovascular complications, but also pay attention to the lower limb vascular lesions. If you feel that your legs are cold, weak and cannot walk far, you should go to a hospital with a peripheral vascular department or vascular surgery department in time to have a lower extremity artery ultrasound, lower extremity artery segmental manometry and other related examinations to detect and diagnose early and take timely treatment measures to avoid more serious lower extremity vascular disease.