The statement “Nucleic acid is more likely to be infected” is incorrect, and the risk of infection from a formal nucleic acid test is very low. The risk of infection is very low with formal nucleic acid testing, as the swabs and pressure plates used by the tester are disposable. Healthcare workers also practice good hand hygiene, and if they are concerned that their hands may be contaminated after the test, they use a quick hand sanitizer to disinfect the palms and backs of their hands in a timely manner. For the test subject, the first thing to do when doing nucleic acid testing is to wear a good mask. Meanwhile, when doing nucleic acid test, try not to touch the tools and equipment of the medical institution, keep a distance of more than 1 meter from other people and do not talk to them during the examination process, and leave the testing site as soon as possible after the examination is completed to avoid lingering. In summary, the risk of infection of formal nucleic acid testing is very small, if the location of the need for nucleic acid sampling, patients should actively cooperate.