Detection of G-difficile usually means that the organism is infected with gram-negative diplococci; common gram-negative diplococci include Moraxella spp. and Neisseria spp. Gram-negative diplococci are diplococci that are negative by Gram staining; Moraxella spp. and Neisseria spp. are common, while Neisseria spp. include Neisseria gonorrhoeae and Neisseria meningitidis. Moraxella spp. are usually referred to as being conditionally pathogenic, and the organism is susceptible to infections in cases of immunocompromise caused by malignancy, chemotherapy, and radiation therapy. Neisseria gonorrhoeae infection occurs after infection of the genitourinary system of purulent infections, such as the common gonorrhea. Most women can develop cervicitis after infection, while men mostly have acute urethritis, whose clinical manifestations are frequent urination, urgency, painful urination, and increased vaginal discharge. If the lab tests show gram-negative diplococcus, you need to go to the hospital in time to check the specific cause and treat it, so as not to delay the condition.