Sudden whole body convulsions at night need to be highly alert to the possibility of seizures. Epilepsy generally has symptoms such as foaming at the mouth, eyes rolled up, teeth closed, and impaired consciousness in addition to whole body convulsions, which need to be observed, and if they are consistent with the above symptoms, it is recommended to go to the hospital immediately to control seizures. In addition, some other factors such as hypocalcemia and cerebrovascular diseases may also cause sudden generalized convulsions at night in bed. 1. Hypocalcemia: When hypocalcemia occurs in the organism, neuromuscular excitability increases, which causes continuous activity of neuromuscular tissues, manifested as convulsions, abnormal sensation and muscle spasms. 2. Drug poisoning: Lead, mercury, alcohol, organophosphorus poisoning, overdose of cholinergic drugs, isoniazid, epinephrine, chlorpromazine, etc., can lead to generalized convulsions; 3, encephalitis: mostly caused by viral infections, which can cause damage to the central nervous system, resulting in edema, apoptosis, necrosis of nerve cells, etc., thus leading to electrophysiological disorders in the brain and generalized convulsions, fever and other symptoms; 4, cerebrovascular diseases: for example, patients with cerebral hemorrhage and cerebral infarction, resulting in impaired brain function and convulsions, sensory impairment, impaired consciousness, etc. Generally found that the whole body convulsions, it is prudent to recommend all to the hospital to check the EEG, cranial CT, etc., to see the specific situation of the nervous system, if there is no abnormality, it will also be more reassuring, if abnormalities are found, it is necessary to actively treat for the cause.