There is no such thing as which is better, Glucosamine Sulfate or Celecoxib. Glucosamine sulfate and Celecoxib are two different drugs, there are big differences in drug indications, pharmacological mechanism, drug composition, etc., need to be based on the patient’s specific type of disease, condition, personal situation and other factors to make a specific choice. Glucosamine sulfate is mainly used for the treatment of primary and secondary osteoarthritis by improving the repair ability of cartilage cells and inhibiting the enzymes that damage cartilage to alleviate joint pain and improve joint mobility, and is composed of glucosamine sulfate. Celecoxib is a common non-steroidal anti-inflammatory drug, through the inhibition of human cyclo-oxygenase to play the role of analgesia, antipyretic, can be used to alleviate a variety of diseases, including osteoarthritis, resulting in pain, fever and other symptoms, the drug component is celecoxib, the drug can be better to alleviate the symptoms, but can not play a role in improving the joint mobility and other effects. Patients with contraindications to both Glucosamine Sulfate and Celecoxib are prohibited from using the drug for treatment. Common adverse drug reactions to glucosamine sulfate are nausea, belching (hiccups), abdominal pain, etc. Common adverse drug reactions to celecoxib are high blood pressure and gastrointestinal bleeding. Glucosamine sulfate and celecoxib should be used under the guidance of a physician, and it is recommended that patients who need to take glucosamine sulfate or celecoxib go to the relevant departments of regular hospitals for consultation, and do not take the drug on their own.