A positive infant primary screen is abnormal and requires further review; if it is still positive, it indicates that the child may have an inherited disease. The initial infant screening is generally for newborns who have breastfed 6-8 times in the first 72 hours of life, and is mainly to check for inherited metabolic diseases, including phenylpropanolone disease and hypothyroidism. Positive test results may also be affected by the screening time, the examination environment and other factors, false positives, at this time need to be further reviewed, if the review results are still positive, it means that the child may be suffering from hereditary metabolic diseases, the need for timely and relevant examinations, active treatment, to avoid affecting the child’s intellectual and physical growth and development.