Uremia without dialysis will prevent the toxins in the body from being discharged, which will cause complications such as metabolic acidosis, uremic encephalopathy and heart failure. 1. Metabolic acidosis: lack of appetite, vomiting, weakness, respiration, etc., which is related to the inhibition of a variety of enzyme activities in the body during acidosis. 2. Uremic encephalopathy: a series of neuropsychiatric symptoms, such as drowsiness, babbling, irritability, mania and so on. In severe cases, convulsions of the limbs may also occur. 3. Heart failure: anuria, decreased urinary discharge of potassium, combined with hyperkalemia, numbness of the limbs, weakness of the lower limbs, slow heartbeat, severe cardiac arrest and other symptoms; water and sodium retention, increasing the burden on the heart to appear heart failure, dyspnea and so on. Long-term high blood pressure will also make the heart overload caused by ventricular wall hypertrophy, leading to heart enlargement, causing cardiac insufficiency. Uremic patients need regular hospitals, follow the doctor’s instructions for standardized treatment, do not be afraid of dialysis, and refused dialysis, so as not to aggravate the condition.