It is generally not recommended that herpes zoster receive cancer chemotherapy at the same time as antiviral therapy. The acute inflammatory skin disease caused by the varicella zoster virus is called herpes zoster. The unilateral blister-like rash is distributed in bands and occurs on the chest and back. Herpes occurs during chemotherapy because of the lowered immunity caused by chemotherapy. Herpes is treated with antiviral therapy and, if necessary, analgesics to relieve pain. After herpes zoster is cured, then continue the anti-cancer chemotherapy. Receiving chemotherapy in the condition of low immunity will affect the effect of chemotherapy, and chemotherapy may lead to the patient’s immune function decreasing again, causing corresponding toxic side effects, which is not conducive to the anti-cancer treatment. If herpes zoster occurs during chemotherapy, it is necessary to consult a doctor as soon as possible to receive professional treatment to avoid delaying the condition.