At present, the most commonly used examination method for breast disease is mammography, so what is the performance of benign and malignant calcifications in mammography? Let’s summarize it below. Benign calcification: often large, rough or round calcifications with clear edges, vascular calcifications appearing as tubular or track-like, fibroid calcifications appearing as rough or vesicular calcifications, ‘ring-shaped’ or ‘eggshell-like calcifications’ commonly found in fatty necrosis or cysts. Intermediate calcifications (suspicious calcifications): These include indeterminate or ambiguous calcifications and coarse inhomogeneous calcifications. The former are morphologically small and ambiguous, with no typical features, and diffuse distribution is often a manifestation of benign calcifications; whereas clustered distribution, regional distribution, linear and segmental distribution need to be considered for clinical biopsy, and calcifications larger than 0.5 mm with irregular morphology may be malignant changes, but are sometimes seen in benign fibrosis, fibroadenomas and post-traumatic mammary glands. Malignant calcifications may appear as granular punctate calcifications of different sizes and shapes, often less than 0.5 mm in diameter, or linear branching calcifications, often discontinuous and less than 0.5 mm in diameter. For example, if the calcification is diffuse or scattered throughout the breast, often bilaterally, such punctate calcification is mostly benign; when polymorphic calcification is diffusely distributed, especially in one side of the breast, malignant changes cannot be excluded. In summary, for the performance of mammographic examination of the breast calcification situation, the actual clinical work is far more complex than the above, which requires the experience of the diagnostic teachers to assess, and again, I salute them.