A 2-second heart hold may be due to coronary artery spasm or other causes such as various heart diseases, secondary conditions, and associated with mood swings. 1. Heart disease: 2 seconds of heart pain may be due to ischemic heart disease, such as coronary artery spasm or coronary artery ischemia, such as hypertension leading to hypertensive heart disease or rheumatic fever leading to rheumatic heart disease, congenital heart disease. It may also be due to arrhythmia, damage to the structure or function of the heart or the heart muscle, all of which can cause vague pain in the heart. 2. Other systemic diseases: If combined with pneumonia, pleural effusion or systemic multi-systemic diseases, such as tumors, tumor infiltration of the heart, tumor cell release, other inflammatory factors on the cardiac myocytes to produce stimulation, which can lead to vague pain in the heart. 3. Others: A few patients may feel vague pain in the heart due to recent stress, anxiety, lack of sleep and poor rest. After resting or removing the relevant triggers, the symptoms can be significantly relieved. The 2-second heart pain can also be seen in other causes, such as frequent attacks should be promptly go to the hospital to identify the cause, under the guidance of the doctor standardized treatment.