Both eszopiclone and zopiclone are sedative-hypnotic drugs, commonly used in the treatment of insomnia, anxiety, depression, etc.. Zopiclone is not significantly different from eszopiclone in terms of efficacy in the treatment of insomnia, but its adverse effects are relatively few and less severe, and its safety is relatively high, while eszopiclone has a better anxiolytic effect, for patients who need to use which drug should be judged according to the condition, and prohibit the use of private, in order to avoid adverse consequences. Eszopiclone belongs to the benzodiazepine class of short-acting sedative-hypnotic drugs, with sedative-hypnotic, muscle relaxation and anticonvulsant effects, can be used to treat insomnia, anxiety, as well as preoperative sedation. For example, for patients who have difficulty falling asleep after taking it helps to improve the sleep effect, improve the sleep structure, and thus improve the sleep state. However, there are certain adverse reactions after taking this drug, such as dizziness, drowsiness, headache, rebound insomnia, etc. Long-term application can produce drug resistance and dependence. For example, elderly people who take the drug the night before may experience light-headedness when they wake up in the morning the next day, which may easily cause falls and bumps. Zopiclone belongs to the non-benzodiazepine class of cyclopyrrolidone drugs medium-acting sedative-hypnotic drugs, which are mostly used for patients with repeated awakenings or early awakenings during nighttime sleep, as well as anxiety groups, etc. However, adverse reactions such as mild dry mouth, bitter mouth, fatigue and drowsiness can occur after using the drug. Therefore, both drugs have their own advantages. For patients to use which drug, they need to choose according to their condition under the guidance of doctors, and not to give up using the drug because of the side effects. During taking the medication, strictly follow the prescribed dosage. If abnormal symptoms occur during the medication, such as heartburn and headache, you should promptly report to your doctor and decide whether to stop or change the medication.