There is no easiest way to rule out tuberculosis, but it can be ruled out by imaging, tuberculin test examination, sputum smear, and surgical examination. 1. Imaging examination: Chest radiographs or CT of lungs are usually used. If there are lesions after imaging examination, further diagnosis is needed. 2. Tuberculin test: Tuberculin test is mainly done by subcutaneous injection of pure protein derivative, and then observe whether there is any redness or hardness at the injection site. 3. Sputum smear: the pathogens can be cultured in the sputum in a special culture container under the premise of certain temperature and humidity and necessary nutrition, and then smear examination can be carried out. 4. Surgical examination: surgical excision of tissue for pathological examination, but this method is rarely used. It is important to note that all of the above tests have the possibility of false negatives, so there is no simplest method, and it is recommended to cooperate with the doctor to conduct a variety of tests.