Eusebio is a combination of estrogen and progestin, which is mainly used for contraception in clinical practice, it is a compounded short-acting contraceptive. Patients are required to take one tablet once a day for 21 days starting on day 1-5 of menstruation. While taking it, patients usually do not experience irregular vaginal bleeding, and they will have their period about 2-3 days after stopping the pill. However, the patient’s menstrual flow is usually reduced after taking Eusebio because the main hormonal component of Eusebio is progestin and the amount of estrogen is very low. Progesterone can counteract estrogen and make the patient’s endometrium thinner, so the patient’s vaginal bleeding is very low after the endometrium peels off. After stopping the medication for 1 week, the patient starts the next cycle of medication again. Patients must be careful not to miss a dose when taking Eusebio, and must make up for the missed dose in time to avoid irregular vaginal bleeding due to fluctuations in hormone levels.