What is brain herniation? When there is a space-occupying lesion in one of the normal cranial cavities, the pressure in that cavity is higher than that of the neighboring cavities, and the brain tissue shifts from the high-pressure area to the low-pressure area, and is squeezed into the nearby physiological foramen or non-physiological foramen, so that part of the brain tissue, nerves, and blood vessels are pressurized, and the circulation of the cerebrospinal fluid becomes impaired and produces a corresponding cluster of symptoms, which is known as a cerebral hernia. Brain herniation is generally caused by a sharp increase in intracranial pressure and is a very critical acute craniocerebral disorder. For the treatment of brain hernia, the acute phase of the disease often requires debridement, which may lead to skull defects. Does the skull have to be replaced after the brain hernia is healed? The answer is yes. For the treatment of brain herniation, debridement often requires the removal of a large area of bone flap, resulting in a large skull defect. Large cranial defects, for one thing, will cause the appearance of the skull is very unattractive, but also vulnerable to external damage, more importantly, the integrity of the closed cranial cavity is destroyed, the environment of the cranial cavity will change, the intracranial pressure becomes unstable, the intracranial blood circulation, the cerebrospinal fluid circulation and so on are disturbed, which will affect the normal performance of the cerebral nerve function, resulting in a series of neurological symptoms, and may even be life-threatening. Therefore, if a large bone flap defect is caused, then cranial bone repair should be carried out in time after the brain hernia is cured. Of course, cranial bone repair is also a relatively routine operation in neurosurgery, and the technology is relatively mature. Patients need to go to a regular hospital and choose an experienced neurosurgeon to operate. In terms of repair material, it is also necessary to choose carefully. At present, the ideal is polyether ether ketone PEEK material, this material is much better than the traditional titanium mesh material, excellent performance, high postoperative comfort, strong protection, effective prevention of various complications, highly respected by doctors and patients.