Thyroid nodule 10mm x 6mm may be palpable by hand if it is in a very shallow location, but not necessarily if it is in a deeper location. Thyroid nodule 10mm x 6mm is not big in itself, but if the location is very shallow, it may be palpable by hand because the nodule is in a relatively shallow location and the epidermal tissues are relatively thin, so the lump can be palpable by hand, but the texture is relatively soft, and it will not usually be too easy to arouse the patient’s awareness. If the thyroid nodule is in a deeper location, even if it is a larger nodule, it may not be possible to feel it with the hand, because when the thyroid nodule is in a deeper location, the hand can only feel the skin, muscles and soft tissues, and it is not possible to accurately identify whether it is a thyroid nodule or not. If you suspect that you have thyroid nodules, you need to consult a doctor in time to further observe the condition through relevant examinations, such as thyroid ultrasound, imaging, etc. In order to exclude malignant lesions, you need to do a puncture cytology or pathology examination if necessary, and understand the cause of the disease under the guidance of the doctor and then target treatment.