Numbness, swelling and pain of the lower limbs may be physiological factors, or pathological factors, common causes are varicose veins of the lower limbs, lower limb venous thrombosis, diabetic peripheral neuropathy and so on. 1. Physiological: After standing for a long time due to exertion, the lower limbs will be numb, swollen and painful due to poor blood return. This situation can be relieved after elevating the lower limbs and resting. 2. Varicose veins of the lower limbs: poor blood return caused by valve dysfunction in the superficial veins of the lower limbs causes blood to stagnate in the veins, resulting in increased venous pressure, which in the long run expands the vein walls, bulges, and tortuously manifests itself in the form of streaks and clumps. It is common in people with heavy physical labor and long time standing. 3. Lower extremity venous thrombosis: thrombus formed in the deep veins of the lower extremity blocks the return of blood, which is manifested by the skin color of the affected area showing bruise-like, mottled, and pain, pressure, and numbness symptoms. 4. Diabetic peripheral neuropathy: it is related to poor blood sugar control. Patients may have bilateral lower limb pain, numbness, sensory abnormalities and other symptoms. In summary, patients should pay attention to the lower limbs of warmth, appropriate rest and exercise. If the numbness, swelling and pain of the lower limbs can not be relieved for a long time, you should go to the hospital in time.