From the classic open, traditional LC, up to the present single-port, transnatural cavity laparoscopic surgery, all show their unique charm and laparoscopic surgery is changing day by day. Recently, we have successfully completed more than 10 cases of single-hole double vision pneumoperitoneum-free laparoscopic cholecystectomy (DPLC) with good clinical results. 1. Traditional cholecystectomy (OC) has been performed for more than 120 years, with mature surgical techniques and reliable efficacy. However, it is traumatic and has many comorbidities. 2.Small incision cholecystectomy (MC), which has been carried out for 25 years, is basically the same technology as OC, except that the incision in the abdominal wall is small (generally <6 cm), which is called in academic circles: small invasive surgery, the efficacy depends on the doctor's skill, and the surgical risk is higher due to exposure and illumination. Wu Wujun, Department of Hepatobiliary Surgery, Shaanxi Provincial People's Hospital 3, trans-laparoscopic cholecystectomy (LC), carried out in China for 19 years, is the classic representative of modern minimally invasive surgery, minimally invasive surgery, reliable efficacy, but must be general anesthesia and carbon dioxide artificial pneumoperitoneum, most of the surgery via 3-4 orifices. 4, DPLC main features: 1, do not need carbon dioxide pneumoperitoneum, most of them can be successfully completed under continuous epidural anesthesia; 2, can be used for the combination of heart and lung diseases of elderly and frail patients with high-risk factors, can be used for re-operation of patients after major upper abdominal surgery and surgery with complex local pathology, can be used for surgery of LC cases requiring intermediate transfer; 3, single orifice, abdominal wall trauma is reduced; no skin preparation, surgery More humane, no stitch removal after surgery, most patients can go to the floor and resume eating and drinking in 8-10 hours after surgery, which reduces the hospitalization time and saves medical costs for patients. 4, DPLC is less traumatic after surgery, with only one mouth in the abdomen, which is more beautiful and more acceptable to patients. Indications: a acute and chronic cholecystitis, including patients with complex local pathological changes, such as purulent cholecystitis leading to perforation, gangrene and gallbladder atrophy, filled stones; b gallbladder polyps, static gallbladder stones; c patients with indications for cholecystectomy, but with excessive obesity, mid- to late-term pregnancy, extra-abdominal hernia, etc., who cannot tolerate CO2 pneumoperitoneum; or patients with a history of abdominal surgery and extensive abdominal adhesions that cannot perform CO2 pneumoperitoneum Patients with a history of abdominal surgery and extensive abdominal adhesions that prevent CO2 pneumoperitoneum; or patients with combined cardiac, pulmonary, or cerebral disease and elderly patients in poor general condition who cannot tolerate general anesthesia or open cholecystectomy; d Patients with preoperative estimate of the possibility of LC in transit; e Patients with gallbladder stones combined with Mirrizzi syndrome type I. Contraindications and precautions: Contraindications: a infectious diseases such as hepatitis A, hepatitis B, AIDS and tuberculosis in active stage; b cirrhosis combined with moderate or severe portal hypertension; c intrahepatic bile duct stones combined with obstruction and hepatic lobe atrophy; d coagulation dysfunction; e malignant lesions of gallbladder or high suspicion of malignant lesions of gallbladder before surgery, and patients with jaundice whose cause has not been identified.