Tobacco was first included as a medicine in the Ming Dynasty medical doctor Zhang Jingyue’s “Jing Yue Quan Shu. Ben Cao Zheng”. By the late Ming and early Qing dynasties, tobacco gradually evolved into a common thing to smoke, from the derivation of dry tobacco, water pipe, snuff, to become a bad lifestyle harmful to health. The medical doctor Wu Cheng in the book “not living in the collection” listed in the chapter of “smoke theory”, put forward the “deficient people, the most easy to quit this” point of view. He believes that “people without disease frequently smoked, solid fluid withered, dark loss of life”, pointing out that smoking is delusional damage to the internal organs, no longevity vices, is one of the causes of internal deficiency. The Qing dynasty doctor Wu Yiluo in the “herbs from the new” will be classified as a poison class, pointed out that smoking can lead to “throat wind sore throat, coughing blood, loss of voice of the disease”, issued a “health people easy far from the” caution. Zhao Xuemin, a medical scientist of the Qing Dynasty, pointed out that tobacco “consumes the lungs and loses blood, and the world suffers from its scourge without realizing it”, and in his book, “Collection of the Materia Medica”, he summarized the hazards of smoking as “injury to qi, injury to the mind, and loss of blood. In his book, “Materia Medica”, he summarized the hazards of smoking as “injury to the qi, injury to the spirit, damage to the blood.